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32
Cat. No. | Product Name | Target | Signaling Pathways |
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T11634 |
IL-15-IN-1
|
IL Receptor; Interleukin | Immunology/Inflammation |
IL-15-IN-1是一种 IL-15依赖性细胞的选择性抑制剂(IC50:0.8 μM)。 | |||
T76892 |
Ordesekimab
AMG 714,PRV-015 |
IL Receptor | Immunology/Inflammation |
Ordesekimab (AMG 714) 是一种人 IgG1κ 抗 IL-15 (Interleukin Related) 单克隆抗体。Ordesekimab 竞争性与 IL-15 结合,会抑制 IL-15 与 IL-2Rβ 和 IL-15 受体复合物的共同 γ 链的相互作用,却不与 IL-15Rα 链发生反应。Ordesekimab 可用于研究无反应性乳糜泻 (NRCD) 。 | |||
T1846 |
Y-320
Y320 |
IL Receptor; Lipase; Interleukin | Immunology/Inflammation; Metabolism |
Y-320 是一种免疫调节剂,能阻碍IL-15刺激CD4 T 细胞后的IL-17的产生,IC50=20~60 nM。 | |||
T77034 |
Inbakicept
N-803 |
||
Inbakicept (ALT-803) 是一种 IL-15超激动剂,由 IL-15突变体和 IL-15Rα-Fc 融合体组成。Inbakicept 可放大抗 CD20单抗介导的 NK 细胞反应和抗体依赖性细胞毒性 (ADCC)。INbakicept 也增加 NK 细胞的脱粒或 IFNγ 的产生。 | |||
T77156 | Depemokimab | ||
Depemokimab (GSK-3511294) 是一种长效的抗IL-15单克隆抗体。Depemokimab 可用于哮喘研究。 | |||
T73014 | NLRP3-IN-15 | ||
NLRP3-IN-15 是一种有效的、选择性的 NLRP3炎症小体抑制剂 (KD: 5.87 μM)。NLRP3-IN-15 抑制 IL-1β 释放,IC50为 0.131 μM。NLRP3-IN-15可用于炎症研究。 | |||
T79362 |
COX-2/15-LOX-IN-4
|
Lipoxygenase | Metabolism |
COX-2/15-LOX-IN-4(compound 5i)是一种针对COX-2和15-LOX的双重抑制剂,其IC50值分别为0.075 μM和1.97 μM。该化合物能有效地阻止LPS诱发的细胞内促炎细胞因子(IL-6, ROS)的产生,表现出明确的抗炎活性。 | |||
T78782 |
PROTAC BTK Degrader-6
|
BTK | Angiogenesis; Tyrosine Kinase/Adaptors |
PROTACBTK Degrader-6 (Compound 15) 为PROTACBTK类降解剂,其DC50为3.18 nM。该化合物展现出抗炎特性,能够抑制NF-κB的激活,并降低促炎细胞因子(如IL-1β、IL-6)的表达。 | |||
T79361 |
COX-2/15-LOX-IN-3
|
Lipoxygenase | Metabolism |
COX-2/15-LOX-IN-3 (compound 5k) 为COX-2/15-LOX的一种双重抑制剂,具有分别为0.075 μM和1.97 μM的IC50值。该化合物能显著抑制LPS诱导的细胞产生促炎细胞因子(IL-6, ROS和NO),表明其具备显著的抗炎活性。 | |||
T79385 |
PDE1-IN-5
|
||
PDE1-IN-5 (Compound 10c) 是一种PDE1C选择性抑制剂,IC50为15 nM。该化合物显示出抗炎活性,能够抑制LPS诱导的iNOS、TNF-α、IL-1α、IL-1β和IL-6表达。在DSS诱导的结肠炎小鼠模型中,PDE1-IN-5对抗炎性肠病(IBD)表现出治疗潜力,并可用于IBD相关研究。 | |||
T60560 | Anti-inflammatory agent 15 | ||
Anti-inflammatory agent 15 (化合物 29) 是有效的抗结核分枝杆菌剂,可用于结核病(TB)的研究。Anti-inflammatory agent 15 抑制 Mtb H37Rv 和 M299生长,MIC50分别为 2.3 和 7.8 μM。Anti-inflammatory agent 15也是一种抗炎剂, 通过抑制 iNOS 的表达来抑制 NO,同时也抑制 TNF-α 和 IL-1β 的产生。 | |||
T75096 | STING agonist-28 | ||
STINGagonist-28 (CF510) 是一种非核苷酸小分子STING 激动剂。STINGagonist-23 激活STING,增加STING、TBK1和IRF3的磷酸化。STINGagonist-23 可促进肿瘤细胞中IFN-β、IL-6、CXCL-10、TNF-α、ISG-15和CCL-5的水平。STINGagonist-23 表现出抗SARS-CoV 系列的活性。 | |||
T75094 | STING agonist-26 | ||
STINGagonist-26 (CF508) 是一种非核苷酸小分子STING 激动剂。STINGagonist-23 激活STING,增加STING、TBK1和IRF3的磷酸化。STINGagonist-23 可促进肿瘤细胞中IFN-β、IL-6、CXCL-10、TNF-α、ISG-15和CCL-5的水平。STINGagonist-23 表现出抗SARS-CoV 系列的活性。 | |||
T75092 | STING agonist-24 | ||
STINGagonist-24 (CF504) 是一种非核苷酸小分子STING 激动剂。STINGagonist-23 激活STING,增加STING、TBK1和IRF3的磷酸化。STINGagonist-23 可促进肿瘤细胞中IFN-β、IL-6、CXCL-10、TNF-α、ISG-15和CCL-5的水平。STINGagonist-23 表现出抗SARS-CoV 系列的活性。 | |||
T73330 |
JAK-IN-24
|
||
JAK-IN-24 是一种 JAK 抑制剂,在 4 μM 或 1 mM ATP 存在时,IC50分别为 0.534 和 24 nM。JAK-IN-24 还抑制 PBMCIL-15诱导的 STAT5磷酸化,IC50为 86.171 nM。 | |||
T75093 | STING agonist-25 | ||
STINGagonist-25 (CF505) 是一种非核苷酸小分子 STING 激动剂。STINGagonist-23 激活 STING,增加 STING、TBK1和 IRF3的磷酸化。STINGagonist-23 可促进肿瘤细胞中IFN-β、IL-6、CXCL-10、TNF-α、ISG-15和CCL-5的水平。STINGagonist-23 表现出抗SARS-CoV 系列的活性。 | |||
T83670 |
F1 TFA
Tat-IKIP (46-60),Tat-Inhibitor of NF-κB Kinase-interacting Peptide |
||
F1是一种抗炎肽,由HIV-1 Tat蛋白质转导域与对应于抑制因子NF-κB激酶-相互作用肽(IKIP)46-60残基的15氨基酸肽链接而成。在5 µM浓度下,F1抑制了小鼠腹腔巨噬细胞中LPS诱导的IκB激酶α(IKKα)和IKKβ的磷酸化以及NF-κB(p65)的核内转移。在体内,F1(5 mg/kg)降低了LPS诱导的脓毒症小鼠模型中IL-6、TNF-α和IL-1β的血清水平,并增加了生存率。 | |||
T75091 | STING agonist-23 | ||
STINGagonist-23 (CF502) 是一种非核苷酸小分子 STING 激动剂。STINGagonist-23 激活 STING,增加 STING、TBK1和 IRF3的磷酸化。STINGagonist-23 可促进肿瘤细胞中 IFN-β、IL-6、CXCL-10、TNF-α、ISG-15和 CCL-5的水平。STINGagonist-23 表现出抗 SARS-CoV 系列的活性。 | |||
T82189 |
HMGB1-IN-2
|
||
HMGB1-IN-2 (compound 15) 是一种针对高度保守的核蛋白 HMGB1 的抑制剂,其在 RAW264.7 细胞中展现出 NO 抑制活性,IC50 为 20.2 μM。 HMGB1-IN-2 (30 μM) 能够减少 IL-1β、TNF-α、caspase-1 p20 的表达,并抑制 NF-κB p65 的磷酸化作用,显示出抗凋亡特性。在脓毒症急性肾损伤模型的小鼠中,HMGB1-IN-2(15 mg/kg;腹腔注射)可有效减轻肾脏伤害。此外,HMGB1-IN-2 对 Huh7 细胞和 A549 细胞的 IC50 分别为 77.0 μM 和 82.0 μM。 | |||
T71884 |
ß-Carboline-1-carboxylic acid
|
||
β-Carboline-1-carboxylic acid is an alkaloid that has been found in P. quassioides and has diverse biological activities. It reduces LPS-induced increases in MCP-1, TNF-α, IL-6, and IL-1β levels in RAW 264.7 cells when used at a concentration of 15 µg/ml and inhibits the epithelial-to-mesenchymal transition (EMT) induced by TGF-β1 in A549 cells. β-Carboline-1-carboxylic acid induces cytotoxicity in CT26.WT, K562, and SGC-7901 cells (IC50s = 14.96, 22.11, and 19.7 µg/ml, respectively) but not Hep... | |||
T35453 |
β-Defensin-4 (human) (trifluoroacetate salt)
|
||
β-Defensin-4 is a peptide with antimicrobial properties that protects the skin and mucosal membranes of the respiratory, genitourinary, and gastrointestinal tracts. It induces migration of monocytes in vitro when used at a concentration of 10 nM but does not affect migration of neutrophils and eosinophils. β-Defensin-4 (30 μg/ml) stimulates gene expression and production of IL-6, IL-10, CXCL10, CCL2, MIP-3α, and RANTES by keratinocytes. It also stimulates calcium mobilization, migration, and pro... | |||
T36629 | Givinostat | ||
Givinostat (ITF-2357) is a HDAC inhibitor with an IC50 of 198 and 157 nM for HDAC1 and HDAC3, respectively. Givinostat (ITF2357) suppresses total LPS-induced IL-1β production robustly compared with the reduction by ITF3056. At 25, 50, and 100 nM, Givinostat reduced IL-1β secretion more than 70%. Givinostat (ITF-2357) suppresses the production of IL-6 in PBMCs stimulated with TLR agonists as well as the combination of IL-12 plus IL-18. IL-6 secretion decreases to 50% at 50 nM Givinostat, but at 1... | |||
T38309 |
LL-37 amide (trifluoroacetate salt)
|
||
LL-37 is a cationic and α-helical antimicrobial peptide expressed in human bone marrow, testis, granulocytes, and gingival epithelium and is upregulated in psoriatic lesions. It inhibits growth of Gram-positive E. coli D21 and Gram-negative B. megatarium in a concentration-dependent manner and LL-37 expression is induced in A549 epithelial cells, alveolar macrophages, neutrophils, and monocyte-derived macrophages following M. tuberculosis infection. LL-37 binds sheep erythrocytes coated with S. ... | |||
T36486 |
Benpyrine
|
||
Benpyrine is a highly specific and orally active TNF-α inhibitor with a KD value of 82.1 μM. Benpyrine tightly binds to TNF-α and blocks its interaction with TNFR1, with an IC50 value of 0.109 μM. Benpyrine has the potential for TNF-α mediated inflammatory and autoimmune disease research[1]. Benpyrine (5-20 μM; 14 hours; RAW264.7 cells) pretreatment results in a dose-dependent decrease in the phosphorylation of IκBα in RAW264.7 cells (stimulated with 10 ng/mL TNF-α or 1 μg/mL LPS). Benpyrine abo... |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-01461 |
IL-15RA & IL-15 Protein, Human, Recombinant (hFc)
IL-15 Receptor α & IL-15... |
Human | HEK293 Cells |
IL15RA is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits to initiate signal transduction. It can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Il15ra is expressed in special cells including a wide variety of Tand B cells and non-lymphoid cells.IL-15 is a cytokine that regulates T cell and natural killer cell activation and proliferation. IL-15 ... | |||
TMPJ-01462 |
IL-15RA & IL-15 Protein, Human, Recombinant - PBS Lyophilized (hFc)
IL15,IL15RA&IL<... |
Human | HEK293 Cells |
IL15RA is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits to initiate signal transduction. It can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Il15ra is expressed in special cells including a wide variety of Tand B cells and non-lymphoid cells.IL-15 is a cytokine that regulates T cell and natural killer cell activation and proliferation. IL-15 ... | |||
TMPY-04632 |
IL-15 Protein, Human, Recombinant
白细胞介素,IL-15,白介素,interleukin 15 |
Human | E. coli |
IL-15 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 12.8 kDa and the accession number is P40933-1. | |||
TMPJ-01099 |
IL-15RA Protein, Human, Recombinant (hFc, Human Cells)
interleukin-15 receptor subunit α,IL15... |
Human | HEK293 Cells |
Interleukin 15 Receptor alpha (IL-15Rα) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Rα chain can bind soluble IL-15 and “transpresent” cytokine to the cells, allowing them to respond to IL-15. Soluble IL-15Rα can function as a specific high-affinity IL-15 antagonist. The soluble IL-15/IL-15Rα complexes exhibit a strong agonistic activity which is mediated through membrane-boun... | |||
TMPY-04049 |
IL-15 Protein, Human, Recombinant (His)
interleukin 15,白细胞介素,白介素,IL-15 |
Human | E. coli |
IL-15 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 14.9 kDa and the accession number is P40933-1. | |||
TMPK-00159 |
IL-15RA Protein, Human, Recombinant (His & Avi)
IL-15 R α,IL-15RA/IL... |
Human | HEK293 Cells |
Interleukin-15 receptor alpha (IL-15R alpha) is a high affinity IL-15 binding protein that is crucial for mediating IL-15 functions such as memory CD8 T cell proliferation and NK, NK/T cell, and intestinal intraepithelial lymphocyte development. IL-15RA Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 21.3 kDa and the accession number is Q13261-1. | |||
TMPK-00160 |
IL-15RA Protein, Human, Recombinant (His & Avi), Biotinylated
MGC104179,IL-15 R α,IL-15 |
Human | HEK293 Cells |
Interleukin-15 receptor alpha (IL-15R alpha) is a high affinity IL-15 binding protein that is crucial for mediating IL-15 functions such as memory CD8 T cell proliferation and NK, NK/T cell, and intestinal intraepithelial lymphocyte development. IL-15RA Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 21.3 kDa and the accession number is Q13261-1. | |||
TMPY-06591 |
IL-15RA Protein, Mouse, Recombinant (aa 1-205, hFc)
interleukin 15 receptor, alpha,interleukin 15 |
Mouse | HEK293 Cells |
IL-15RA Protein, Mouse, Recombinant (aa 1-205, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.10 kDa and the accession number is Q60819-1. | |||
TMPJ-00154 |
IL-15RA Protein, Mouse, Recombinant (hFc, Human Cells)
sIL-15 receptor subunit α,Il1... |
Mouse | HEK293 Cells |
Mouse interleukin-15 receptor subunit alpha, also known as Il15ra, is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits (Common gamma chain, or gamma c) to initiate signal transduction. It can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Il15ra is expressed in special cells including a wide variety of Tand B cells and non-lymphoid cells. Human Il... | |||
TMPK-00320 |
IL-2 R beta/CD122 Protein, Human, Recombinant (His & Avi)
IL-2 R β/CD122,IL-15 R beta,RP5-1... |
Human | HEK293 Cells |
IL-2 R beta/CD122 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 27.5 kDa and the accession number is P14784. | |||
TMPK-00321 |
IL-2 R beta/CD122 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
IL-2 R beta,IL-2R subunit beta,IL... |
Cynomolgus | HEK293 Cells |
IL-2 R beta/CD122 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 25.6 kDa and the accession number is Q38J85. | |||
TMPY-06531 |
IL-15 & IL-15RA Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 Cells |
IL-15 & IL-15RA Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.46 kDa and the accession number is P48346-1 & Q60819-1. | |||
TMPY-06020 |
IL-15 & IL-15RA Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
IL-15 & IL-15RA Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47.9 kDa and the accession number is NP_002180.1&NP_000576.1. | |||
TMPH-02441 |
IL-15 Protein, Rhesus macaque, Recombinant (His)
|
Rhesus | P. pastoris (Yeast) |
Cytokine that stimulates the proliferation of T-lymphocytes. Stimulation by IL15 requires interaction of IL15 with components of the IL2 receptor, including IL2RB and probably IL2RG but not IL2RA. In neutrophils, stimulates phagocytosis probably by signaling through the IL15 receptor, composed of the subunits IL15RA, IL2RB and IL2RG, which results in kinase SYK activation. IL-15 Protein, Rhesus macaque, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 1... | |||
TMPY-06587 |
IL-15RA Protein, Human, Recombinant (His)
interleukin 15 receptor, alpha,interleukin 15 |
Human | E. coli |
IL-15RA Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 20.22 kDa and the accession number is NP_002180.1. | |||
TMPY-06634 |
IL-15RA Protein, Human, Recombinant (hFc & Avi), Biotinylated
CD215,interleukin 15 receptor, α,interleuk... |
Human | HEK293 Cells |
IL-15RA Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 46.92 kDa and the accession number is NP_002180.1. | |||
TMPY-05741 |
IL-15RA Protein, Human, Recombinant (aa 31-205, hFc)
interleukin 15 receptor, alpha,CD215,inter... |
Human | HEK293 Cells |
IL-15RA Protein, Human, Recombinant (aa 31-205, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.22 kDa and the accession number is Q13261-1. | |||
TMPJ-00890 |
IL-13 Protein, Mouse, Recombinant (aa 26-131, His)
Interleukin-13,T-Cell Activation Protein P600,白细胞介素,IL |
Mouse | HEK293 Cells |
IL-13 Protein, Mouse, Recombinant (aa 26-131, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 15-30 KDa and the accession number is P20109. | |||
TMPY-00524 |
IL-7 Protein, Mouse, Recombinant
Il-7,A630026I06Rik,interleukin 7,hlb368 |
Mouse | E. coli |
IL-7 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15 kDa and the accession number is P10168. | |||
TMPJ-01339 |
IL-22 Protein, Mouse, Recombinant (E. coli)
IL-TIF Alpha,Il22a,IL-22,Il |
Mouse | E. coli |
IL-22 Protein, Mouse, Recombinant (E. coli) is expressed in E. coli expression system. The predicted molecular weight is 15 KDa and the accession number is Q9JJY9. | |||
TMPY-02809 |
IL-21 Protein, Canine, Recombinant
interleukin 21,白细胞介素,白介素 |
Canine | E. coli |
IL-21 Protein, Canine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15 kDa and the accession number is Q6L7I9. | |||
TMPY-04042 |
IL-7 Protein, Rat, Recombinant
interleukin 7,白细胞介素,白介素 |
Rat | E. coli |
IL-7 Protein, Rat, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15 kDa and the accession number is Q91Y32. | |||
TMPY-01966 |
IL-17F Protein, Mouse, Recombinant
IL-17F,C87042,interleukin 17F |
Mouse | E. coli |
IL-17F Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15 kDa and the accession number is Q7TNI7-1. | |||
TMPJ-01056 |
IL-18 Protein, Mouse, Recombinant (His)
Interferon γ-inducing factor,Interleukin-1 gamma,Igif,IL... |
Mouse | E. coli |
Interleukin-18 (IL-18)is a protein which belongs to the IL-1 family. It is expressed as a 24 kDa precursor by endothelial and epithelial cells, keratinocytes, gamma δ T cells, and phagocytes. Mature mouse IL-18 shares 63% and 91% amino acid sequence identity with mouse and rat IL-18, respectively. IL-18 binds to the widely expressed IL-18 R alpha which recruits IL-18 R beta to form the signaling receptor complex. Its bioactivity is negatively regulated by interactions with IL-18 binding proteins... | |||
TMPK-00084 |
IL-17C Protein, Human, Recombinant (His & Avi)
IL-17C,Cytokine CX2,IL17C,CX2,IL-... |
Human | HEK293 Cells |
Interleukin‑17C (IL‑17C) is a 15‑20 kDa glycosylated cytokine that plays an important role in mucosal immunity and chronic inflammation. The six IL‑17 cytokines (IL‑17A‑F) are encoded by separate genes but adopt a conserved cystine knot fold. IL‑17C is Cytokine that plays a crucial role in innate immunity of the epithelium, including to intestinal bacterial pathogens, in an autocrine manner. Stimulates the production of antibacterial peptides and proinflammatory molecules for host defense by sig... | |||
TMPJ-00239 |
IL-2RG Protein, Mouse, Recombinant (aa 25-263, hFc)
Il2rg,Interleukin 2 receptor, gamma chain, isoform ... |
Mouse | HEK293 Cells |
The Interleukin-2 receptor gamma chain (IL-2 Rγ, CD132) of the high affinity functional mouse IL-2 receptor complex is a member the hematopoietin receptor family. It is expressed on most lymphocyte (white blood cell) populations, and its gene is found on the X-chromosome of mammals. Common IL2 receptor-γ Chain is required for IL-2 receptor signaling. Besides IL-2, the Common IL2 receptor-γ chain has been shown to be a component of the functional receptor complexes for IL-4, IL-7, IL-9 and IL-15.... | |||
TMPJ-01316 |
IL-21 Protein, Mouse, Recombinant (His)
白细胞介素,IL-21,Interleukin-21,白介素,IL21 |
Mouse | E. coli |
Interleukin-21(IL-21) is an approximately 14 kDa cytokine which belongs to the IL-15/IL-21 family. Mature mouse IL-21 shares 66%,59%, 58%, and 88% aa sequence identity with mature canine, human, rabbit, and rat IL-21, respectively. IL-21 is produced by activated T follicular helper cells (Tfh), Th17 cells, and NKT cells. It exerts its biological effects through a heterodimeric receptor complex (IL-21 specific IL-21 R). IL-21 is a cytokine that has potent regulatory effects on cells of the immun... | |||
TMPJ-00832 |
Granzyme D/GZMD Protein, Mouse, Recombinant (His)
Granzyme D,Gzmd |
Mouse | HEK293 Cells |
Granzyme D is a member of the granzyme family of the serine proteases which plays a role in the induction of apoptosis. T cells, lymphohematopoietic stromal cells, and granulated metrial gland cells express granzyme D, but the function of granzyme D is unknown. Previous studies reported that granzyme D is developmentally regulated during pregnancy together with granzymes E, F, and G in granulated metrial gland cells and is upregulated by IL-2 and IL-15. Granzyme D was also suggested to have a ro... | |||
TMPY-00803 |
Fibronectin Protein, Human, Recombinant (aa 607-1265, His)
GFND,LETS,ED-B,fibronectin 1,CIG,GFND2,FNZ,FINC,FN,MSF |
Human | HEK293 Cells |
Fibronectin Protein, Human, Recombinant (aa 607-1265, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 73.2 kDa and the accession number is P02751-15. | |||
TMPY-05562 |
Fibronectin Protein, Human, Recombinant (aa 1722-1811, His)
fibronectin 1,ED-B,CIG,FNZ,MSF,FN,FINC,GFND,LETS,GFND2 |
Human | HEK293 Cells |
Fibronectin Protein, Human, Recombinant (aa 1722-1811, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 11.3 kDa and the accession number is P02751-15. | |||
TMPK-01416 |
HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi), Biotinylated
MHC,SARS-CoV-2 epitope |
Human | HEK293 Cells |
HLA-B*15:01 is strongly associated with asymptomatic infection with SARS-CoV-2 and is likely to be involved in the mechanism underlying early viral clearance. T cells from pre-pandemic individuals carrying HLA-B*15:01 were reactive to the immunodominant SARS-CoV-2 S-derived peptide NQKLIANQF, and 100% of the reactive cells displayed memory phenotype. | |||
TMPK-01412 |
HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi)
SARS-CoV-2 epitope,MHC |
Human | HEK293 Cells |
HLA-B*15:01 is strongly associated with asymptomatic infection with SARS-CoV-2 and is likely to be involved in the mechanism underlying early viral clearance. T cells from pre-pandemic individuals carrying HLA-B*15:01 were reactive to the immunodominant SARS-CoV-2 S-derived peptide NQKLIANQF, and 100% of the reactive cells displayed memory phenotype. |